Modeling and Simulation of Acetaminophen Pharmacokinetics and Hepatic Biomarkers After Overdoses of ExtendedRelease and ImmediateRelease Formulations in Healthy Adults Using the Quantitative Systems Toxicology Software Platform DILIsym Beaudoin The molecular mechanisms of acetaminophen induced hepatotoxicity and its potential therapeutic targets Guangwen Luo, Lili Huang, Zhaowei Zhang, 2023 Acetaminophen Overdose Reveals PAR4 as a Low Expressing but Potent Receptor on the Hepatic Endothelium in Mice Arteriosclerosis, Thrombosis, and Vascular Biology Sex differences in glutathione metabolism and acetaminophen toxicity
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tylenol depletes glutathione pubmed Acetaminophen causes neurodevelopmental injury in susceptible babies and children: no valid rationale for controversy