Silymarin prevents acetaminophen induced hepatotoxicity via up regulation of the glutathione conjugation capacity in mice ScienceDirect View of Acetaminophen, the missing anion gap in the patient with metabolic acidosis The Southwest journal of medicine Correct Answer: B. N acetylcysteine (NAC) Why is this High Yield? Acetaminophen (Paracetamol) is widely used, making toxicity a common ER presentation. 1. Mechanism of Toxicity: Acetaminophen is metabolized in the liver. PDF) A review of the evidence concerning hepatic glutathione depletion and susceptibility to liver toxicity after paracetamol overdose
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paracetamol and glutathione depletion Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential